PRODUCTS
PRODUCTS | MEDINUTREX
RED ORANGE EXTRACT®
All natural health benefits from blood orange
Red orange extract is obtained from three varieties of sicilian blood oranges: Tarocco, Moro and Sanguinello. These orange varieties grow in Italy, in particular in the eastern part of Sicily, where the pedoclimatic conditions and the presence of the volcano Etna , makes it particularly suitable for their cultivation.
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PRODUCTS | MEDINUTREX
VERDELLIMON®
FROM VERDELLO LEMON A VALID CONTRIBUTION TO FIGHT OXIDATIVE STRESS
VERDELLIMON is an extract derived from the Sicilian Verdello lemon, a fruit with a smooth green skin and an intense aroma, produced by the summer flowering of the plant.
PRODUCTS | MEDINUTREX
PRODUCTS | MEDINUTREX
DERMOGRANATE®
DERMOGRANATE®
A source of phytocomplexes essential for the skin and a natural help against inflammation
A source of phytocomplexes essential for the skin and a natural help against inflammation
DERMOGRANATE is an extract derived from pomegranate, a charming red-brown fruit that is shaped like an apple with grains.
DERMOGRANATE is an extract derived from pomegranate, a charming red-brown fruit that is shaped like an apple with grains.
PRODUCTS | MEDINUTREX
PRODUCTS | MEDINUTREX
MEDGRANATE®
MEDGRANATE®
The synergistic action of the pomegranate constituents makes it a natural option for the treatment of prostate inflammation
The synergistic action of the pomegranate constituents makes it a natural option for the treatment of prostate inflammation
MEDGRANATE derives from pomegranate, a fruit of great interest due to its multiple beneficial effects on human health.
MEDGRANATE derives from pomegranate, a fruit of great interest due to its multiple beneficial effects on human health.
NATIONAL AND INTERNATIONAL CUSTOMERS
NATIONAL AND INTERNATIONAL CUSTOMERS
INNOVAZIONE
INNOVAZIONE
Experimental studies performed on BLORANGEX demonstrate that, thanks its the presence of antioxidant biocompounds, the extract exerts an anti-inflammatory function. The extract is also able to decrease the accumulation of fat in human liver cells (HepG2) treated with FFA, used as a model of hepatic steatosis. Furthermore, studies conducted on a red orange extract demonstrate that it is able to reduce solar erythema caused by exposure to UV-B radiation.
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CONTACTS
CONTACTS
MEDINUTREX
Contact us: +393913559488
Email: info@medinutrex.com
MEDINUTREX
Contact us: +393913559488
Email: info@medinutrex.com
ALL NATURAL HEALTH BENEFITS FROM BLOOD ORANGE
Medinutrex is an innovative company which operates in the food, nutraceutical and cosmetic fields.
Medinutrex is an innovative company which operates in the food, nutraceutical and cosmetic fields.
BLORANGEX®
medinutrex @ All Right Reserved 2025 | Website created by Flazio Experience
medinutrex @ All Right Reserved 2025 | Website created by Flazio Experience
Description
Botanical name: Citrus Sinensis L. Osbeck
Origin: Italy, Sicily
Appearance: red powder
BLORANGEX is obtained from three varieties of sicilian blood oranges: Tarocco, Moro and Sanguinello. These orange varieties grow in Italy, in particular in the eastern part of Sicily, where the pedoclimatic conditions and the presence of the volcano Etna , makes it particularly suitable for their cultivation.
The feature of red oranges is the presence of high amounts of anthocyanin, a family of antioxidant pigments that cannot be found in other citrus, responsible for the deep red hue of the fruit. Anthocyanins develop when citrus ripen during warm days tempered with cooler nights, acting as a fruit protective system against extreme climatic fluctuations that occur in Sicily’s Etna area.
Together with other flavonoids and hydroxycinnamic acids, anthocyanins represent the characteristic bioactive compounds of blood oranges. They are associated with antioxidant properties, prevention of cardiovascular disease, hypertension, type 2 diabetes and cancer. These biocompounds are also used in the treatment of capillary fragility and other diseases, whose etiology is attributable to the destructive action of free radicals. Furthermore, it has been demonstrated that a standardized extract of blood oranges, rich in anthocyanins, is able to increase the antioxidant defenses in humans affected by diabetes, smokers and in those subjects who practice competitive sports.
The extract is standardized in anthocyanins and flavanones
BENEFITS
Skin protection from UV rays
Counteract skin hyperpigmentation
Antioxidant (reduces oxidative stress)
Anti-aging
Anti-inflammatory
BIOACTIVITY
The three varieties of blood oranges, namely Tarocco, Moro and Sanguinello, are particularly rich in anthocyanins. Ten different molecules have been identified in blood oranges, seven of which are derivatives of cyanidin and three derivatives of delphinidin. Among them, the most representative are cyanidin-3- glucoside and cyanidin-3- 6 ”-malonylglucoside. They act synergistically with the glycoside flavanones (hesperidin, narirutin and didymine), hydroxycinnamic acids (caffeic, coumaric, ferulic and synapic) and vitamin C, and play a key role in the protection of our body from the effects of free radicals, which are the cause of degenerative diseases and skin aging.
SCIENTIFIC PAPERS ON BLORANGEX
Experimental studies performed on BLORANGEX demonstrate that, thanks its the presence of antioxidant biocompounds, the extract exerts an anti-inflammatory function. The extract is also able to decrease the accumulation of fat in human liver cells (HepG2) treated with FFA, used as a model of hepatic steatosis. Furthermore, studies conducted on a red orange extract demonstrate that it is able to reduce solar erythema caused by exposure to UV-B radiation.
-"Beneficial Effects of Standardized Extracts from Wastes of Red Oranges and Olive Leaves"
I. Burò, V. Consoli, A. Castellano, L. Vanella and V. Sorrenti (2022), Antioxidants, 11, 1496. https://doi.org/10.3390/antiox11081496
-"In vitro antioxidant activity and in vivo photoprotective effect of a red orange extract"
F. Bonina, A. Saija, A . Tomaino, R. Lo Cascio, P. Rapisarda, J. D. Dederen (1998)
International Journal of Cosmetic Science 20, 331–342
Scientific article: “Beneficial Effects of Standardized Extracts from Wastes of Red Oranges and Olive Leaves”
The results show that the synergy between the bioactive compounds of the extract, flavonoids, anthocyanins, hydroxycinnamic acids, exerts a strong activity against free radicals. The extract acts also as anti-inflammatory, increasing the levels of OH-1.
At a concentration of 3 mg/mL, BLORANGEX is able to reduce the lipid drops accumulation caused by the treatment of HepG2
cells with 0.75 and 1 mM FFA.
Oil Red O’ staining on HepG2 treated for 72 h with FFA 0.75 Mm and 1 mM in the absence and in presence of a higher concentration (3 mg/mL) of BLORANGEX
Scientific article: "In vitro antioxidant activity and in vivo photoprotective effect of a red orange extract"
The experimental work has been conducted on human volounteers exposed to solar radiations. It has been demonstrated that, using a formulation containing a red orange extract as post-treatment to sun exposure, it is able to reduce the extent of erythema caused by UV-B radiation.
The Red Orange Extract protective effects appear greater than another natural antioxidant (Tocopherol) commonly employed in cosmetic formulations.
This suggests the use of the extract as anti-photoageing and after-sun cosmetic product.
Typical trend of erythema index variation (∆EI) vs time. ROE or TOC solutions were applied to skin sites immediately after exposure to UV-B radiations
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